Prognostic Factors and Recurrence in Breast Cancer: Experience at the National Cancer Institute of Mexico

The purpose of this study was to analyze the prognostic and predictive factors that relate to locoregional or distant recurrences in breast cancer patients who have been treated at the National Cancer Institute of Mexico. Multivariate, time-dependent Cox regression analyses indicate that the pN stat...

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Detalles Bibliográficos
Autores principales: Stankov, A., Bargallo-Rocha, J. E., Silvio, A. Ñamendys-Silva, Ramirez, M. T., Stankova-Ninova, K., Meneses-Garcia, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2012
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3399427/
https://www.ncbi.nlm.nih.gov/pubmed/22830047
http://dx.doi.org/10.5402/2012/825258
Descripción
Sumario:The purpose of this study was to analyze the prognostic and predictive factors that relate to locoregional or distant recurrences in breast cancer patients who have been treated at the National Cancer Institute of Mexico. Multivariate, time-dependent Cox regression analyses indicate that the pN status (positive versus negative lymph node; P = 0.003; HR (hazard ratio), 3.47; CI (confidence interval), 1.52–7.91) and the pathological complete response of the patient to neoadjuvant chemotherapy (yes versus no; P = 0.061; HR, 0.38; CI, 0.14–1.04) were important prognostic factors for recurrence.

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