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Refractory Clostridium difficile Infection Successfully Treated with Tigecycline, Rifaximin, and Vancomycin
The occurrence of Clostridium difficile colitis is on the rise and has become more difficult to manage with standard therapy. Thus, the need for alternative treatments is essential. Tigecycline is a glycylcycline antibiotic that has been shown to be effective against C. difficile through several pub...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3399506/ https://www.ncbi.nlm.nih.gov/pubmed/22829841 http://dx.doi.org/10.1155/2012/702910 |
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author | Lao, Dominador Chiang, Tom Gomez, Eric |
author_facet | Lao, Dominador Chiang, Tom Gomez, Eric |
author_sort | Lao, Dominador |
collection | PubMed |
description | The occurrence of Clostridium difficile colitis is on the rise and has become more difficult to manage with standard therapy. Thus, the need for alternative treatments is essential. Tigecycline is a glycylcycline antibiotic that has been shown to be effective against C. difficile through several published case reports and in in vitro studies. We present a case of C. difficile colitis that failed to respond to metronidazole and oral vancomycin therapy, but improved on a combination of rifaximin, tigecycline, and vancomycin. |
format | Online Article Text |
id | pubmed-3399506 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-33995062012-07-24 Refractory Clostridium difficile Infection Successfully Treated with Tigecycline, Rifaximin, and Vancomycin Lao, Dominador Chiang, Tom Gomez, Eric Case Rep Med Case Report The occurrence of Clostridium difficile colitis is on the rise and has become more difficult to manage with standard therapy. Thus, the need for alternative treatments is essential. Tigecycline is a glycylcycline antibiotic that has been shown to be effective against C. difficile through several published case reports and in in vitro studies. We present a case of C. difficile colitis that failed to respond to metronidazole and oral vancomycin therapy, but improved on a combination of rifaximin, tigecycline, and vancomycin. Hindawi Publishing Corporation 2012 2012-07-09 /pmc/articles/PMC3399506/ /pubmed/22829841 http://dx.doi.org/10.1155/2012/702910 Text en Copyright © 2012 Dominador Lao II et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Lao, Dominador Chiang, Tom Gomez, Eric Refractory Clostridium difficile Infection Successfully Treated with Tigecycline, Rifaximin, and Vancomycin |
title | Refractory Clostridium difficile Infection Successfully Treated with Tigecycline, Rifaximin, and Vancomycin |
title_full | Refractory Clostridium difficile Infection Successfully Treated with Tigecycline, Rifaximin, and Vancomycin |
title_fullStr | Refractory Clostridium difficile Infection Successfully Treated with Tigecycline, Rifaximin, and Vancomycin |
title_full_unstemmed | Refractory Clostridium difficile Infection Successfully Treated with Tigecycline, Rifaximin, and Vancomycin |
title_short | Refractory Clostridium difficile Infection Successfully Treated with Tigecycline, Rifaximin, and Vancomycin |
title_sort | refractory clostridium difficile infection successfully treated with tigecycline, rifaximin, and vancomycin |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3399506/ https://www.ncbi.nlm.nih.gov/pubmed/22829841 http://dx.doi.org/10.1155/2012/702910 |
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