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Anti-Proliferative Effect of Cytohesin Inhibition in Gefitinib-Resistant Lung Cancer Cells

Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKI), such as gefitinib, have been proven to efficiently inhibit the proliferation of a subset of non small-cell lung cancers (NSCLC). Unfortunately, the majority of NSCLC expressing wild type EGFR is primarily resistant to EGFR-TKI...

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Detalles Bibliográficos
Autores principales: Bill, Anke, Schmitz, Anton, König, Katharina, Heukamp, Lukas C., Hannam, Jeffrey S., Famulok, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3399819/
https://www.ncbi.nlm.nih.gov/pubmed/22815959
http://dx.doi.org/10.1371/journal.pone.0041179