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MicroRNA-122 Down-Regulation Is Involved in Phenobarbital-Mediated Activation of the Constitutive Androstane Receptor

Constitutive androstane receptor (CAR) is a nuclear receptor that regulates the transcription of target genes, including CYP2B and 3A. Phenobarbital activates CAR, at least in part, in an AMP-activated protein kinase (AMPK)-dependent manner. However, the precise mechanisms underlying phenobarbital a...

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Detalles Bibliográficos
Autores principales:	Shizu, Ryota, Shindo, Sawako, Yoshida, Takemi, Numazawa, Satoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3399820/ https://www.ncbi.nlm.nih.gov/pubmed/22815988 http://dx.doi.org/10.1371/journal.pone.0041291

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