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Hemoglobin Interactions with αB Crystallin: A Direct Test of Sensitivity to Protein Instability
As a small stress response protein, human αB crystallin, detects protein destabilization that can alter structure and function to cause self assembly of fibrils or aggregates in diseases of aging. The sensitivity of αB crystallin to protein instability was evaluated using wild-type hemoglobin (HbA)...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3399823/ https://www.ncbi.nlm.nih.gov/pubmed/22815750 http://dx.doi.org/10.1371/journal.pone.0040486 |