Transcriptional Repression of the Dspp Gene Leads to Dentinogenesis Imperfecta Phenotype in Col1a1-Trps1 Transgenic Mice

Dentinogenesis imperfecta (DGI) is a hereditary defect of dentin, a calcified tissue that is the most abundant component of teeth. Most commonly, DGI is manifested as a part of osteogenesis imperfecta (OI) or the phenotype is restricted to dental findings only. In the latter case, DGI is caused by m...

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Detalles Bibliográficos
Autores principales: Napierala, Dobrawa, Sun, Yao, Maciejewska, Izabela, Bertin, Terry K, Dawson, Brian, D'Souza, Rena, Qin, Chunlin, Lee, Brendan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2012
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3399940/
https://www.ncbi.nlm.nih.gov/pubmed/22508542
http://dx.doi.org/10.1002/jbmr.1636

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