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The imbalance between Treg and Th17 cells caused by FTY720 treatment in skin allograft rejection

OBJECTIVES: FTY720 modulates CD4(+)T cells by the augmentation of regulatory T cell activity, secretion of suppressive cytokines and suppression of IL-17 secretion by Th17 cells. To further understand the process of graft rejection/acceptance, we evaluated skin allograft survival and associated even...

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Detalles Bibliográficos
Autores principales:	Commodaro, Alessandra Gonçalves, Pedregosa, Juliana Figueredo, Peron, Jean Pierre, Brandão, Wesley, Rizzo, Luiz Vicente, Bueno, Valquiria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2012
Materias:	Basic Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400173/ https://www.ncbi.nlm.nih.gov/pubmed/22892927 http://dx.doi.org/10.6061/clinics/2012(07)17

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