Wound-healing and benzodiazepines: does sleep play a role in this relationship?

Patients who have suffered burns frequently experience psychological consequences, among which anxiety disorders are prominent. Benzodiazepines are commonly administered to treat these symptoms. The effects of benzodiazepines on healing may not be direct but rather are modulated by alterations of th...

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Detalles Bibliográficos
Autores principales: Egydio, Flavia, Pires, Gabriel Natan, Tufik, Sergio, Andersen, Monica Levy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400176/
https://www.ncbi.nlm.nih.gov/pubmed/22892930
http://dx.doi.org/10.6061/clinics/2012(07)20
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author Egydio, Flavia
Pires, Gabriel Natan
Tufik, Sergio
Andersen, Monica Levy
author_facet Egydio, Flavia
Pires, Gabriel Natan
Tufik, Sergio
Andersen, Monica Levy
author_sort Egydio, Flavia
collection PubMed
description Patients who have suffered burns frequently experience psychological consequences, among which anxiety disorders are prominent. Benzodiazepines are commonly administered to treat these symptoms. The effects of benzodiazepines on healing may not be direct but rather are modulated by alterations of the sleep architecture. This hypothesis is supported by studies that demonstrate the effects of benzodiazepines on the immune system and the inflammatory profile under both normal sleep conditions and during sleep deprivation, particularly rapid eye movement sleep deprivation.
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spelling pubmed-34001762012-07-20 Wound-healing and benzodiazepines: does sleep play a role in this relationship? Egydio, Flavia Pires, Gabriel Natan Tufik, Sergio Andersen, Monica Levy Clinics (Sao Paulo) Review Patients who have suffered burns frequently experience psychological consequences, among which anxiety disorders are prominent. Benzodiazepines are commonly administered to treat these symptoms. The effects of benzodiazepines on healing may not be direct but rather are modulated by alterations of the sleep architecture. This hypothesis is supported by studies that demonstrate the effects of benzodiazepines on the immune system and the inflammatory profile under both normal sleep conditions and during sleep deprivation, particularly rapid eye movement sleep deprivation. Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2012-07 /pmc/articles/PMC3400176/ /pubmed/22892930 http://dx.doi.org/10.6061/clinics/2012(07)20 Text en Copyright © 2012 Hospital das Clínicas da FMUSP http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Egydio, Flavia
Pires, Gabriel Natan
Tufik, Sergio
Andersen, Monica Levy
Wound-healing and benzodiazepines: does sleep play a role in this relationship?
title Wound-healing and benzodiazepines: does sleep play a role in this relationship?
title_full Wound-healing and benzodiazepines: does sleep play a role in this relationship?
title_fullStr Wound-healing and benzodiazepines: does sleep play a role in this relationship?
title_full_unstemmed Wound-healing and benzodiazepines: does sleep play a role in this relationship?
title_short Wound-healing and benzodiazepines: does sleep play a role in this relationship?
title_sort wound-healing and benzodiazepines: does sleep play a role in this relationship?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400176/
https://www.ncbi.nlm.nih.gov/pubmed/22892930
http://dx.doi.org/10.6061/clinics/2012(07)20
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