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Transcriptional Regulation of the p53 Tumor Suppressor Gene in S-Phase of the Cell-Cycle and the Cellular Response to DNA Damage

The p53 tumor suppressor induces the transcription of genes that negatively regulate progression of the cell cycle in response to DNA damage or other cellular stressors and thus participates in maintaining genome stability. Numerous studies have demonstrated that p53 transcription is activated befor...

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Detalles Bibliográficos
Autores principales:	Reisman, David, Takahashi, Paula, Polson, Amanda, Boggs, Kristy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400299/ https://www.ncbi.nlm.nih.gov/pubmed/22830025 http://dx.doi.org/10.1155/2012/808934

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