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A Cytotoxic Type III Secretion Effector of Vibrio parahaemolyticus Targets Vacuolar H(+)-ATPase Subunit c and Ruptures Host Cell Lysosomes

Vibrio parahaemolyticus is one of the human pathogenic vibrios. During the infection of mammalian cells, this pathogen exhibits cytotoxicity that is dependent on its type III secretion system (T3SS1). VepA, an effector protein secreted via the T3SS1, plays a major role in the T3SS1-dependent cytotox...

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Detalles Bibliográficos
Autores principales:	Matsuda, Shigeaki, Okada, Natsumi, Kodama, Toshio, Honda, Takeshi, Iida, Tetsuya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400558/ https://www.ncbi.nlm.nih.gov/pubmed/22829766 http://dx.doi.org/10.1371/journal.ppat.1002803

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