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Decreased 5-Hydroxymethylcytosine Is Associated with Neural Progenitor Phenotype in Normal Brain and Shorter Survival in Malignant Glioma
Epigenetic modification of DNA by cytosine methylation to produce 5-methylcytosine (5mC) has become well-recognized as an important epigenetic process in human health and disease. Recently, further modification of 5mC by the ten eleven translocated (TET) family of enzymes to produce 5-hydroxymethylc...
Autores principales: | Orr, Brent A., Haffner, Michael C., Nelson, William G., Yegnasubramanian, Srinivasan, Eberhart, Charles G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400598/ https://www.ncbi.nlm.nih.gov/pubmed/22829908 http://dx.doi.org/10.1371/journal.pone.0041036 |
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