Glycogen Synthase Kinase-3 Inhibition Sensitizes Pancreatic Cancer Cells to TRAIL-Induced Apoptosis

Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) induces apoptosis in a variety of cancer cell lines with little or no effect on normal cells. However, its effect is limited as some cancers including pancreatic cancer show de novo resistance to TRAIL induced apoptosis. In this study w...

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Detalles Bibliográficos
Autores principales: Mamaghani, Shadi, Simpson, Craig D., Cao, Pinjiang M., Cheung, May, Chow, Sue, Bandarchi, Bizhan, Schimmer, Aaron D., Hedley, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400624/
https://www.ncbi.nlm.nih.gov/pubmed/22829912
http://dx.doi.org/10.1371/journal.pone.0041102

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