Glucopyranosyl Lipid Adjuvant (GLA), a Synthetic TLR4 Agonist, Promotes Potent Systemic and Mucosal Responses to Intranasal Immunization with HIVgp140

Successful vaccine development against HIV will likely require the induction of strong, long-lasting humoral and cellular immune responses in both the systemic and mucosal compartments. Based on the known immunological linkage between the upper-respiratory and urogenital tracts, we explored the pote...

Descripción completa

Detalles Bibliográficos
Autores principales: Arias, Mauricio A., Van Roey, Griet A., Tregoning, John S., Moutaftsi, Magdalini, Coler, Rhea N., Windish, Hillarie P., Reed, Steven G., Carter, Darrick, Shattock, Robin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400629/
https://www.ncbi.nlm.nih.gov/pubmed/22829921
http://dx.doi.org/10.1371/journal.pone.0041144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400629/
https://www.ncbi.nlm.nih.gov/pubmed/22829921
http://dx.doi.org/10.1371/journal.pone.0041144

Ejemplares similares