The Physiological Effects of Deleting the Mouse Slc30a8 Gene Encoding Zinc Transporter-8 Are Influenced by Gender and Genetic Background

OBJECTIVE: The SLC30A8 gene encodes the islet-specific transporter ZnT-8, which is hypothesized to provide zinc for insulin-crystal formation. A polymorphic variant in SLC30A8 is associated with altered susceptibility to type 2 diabetes. Several groups have examined the effect of global Slc30a8 gene...

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Detalles Bibliográficos
Autores principales: Pound, Lynley D., Sarkar, Suparna A., Ustione, Alessandro, Dadi, Prasanna K., Shadoan, Melanie K., Lee, Catherine E., Walters, Jay A., Shiota, Masakazu, McGuinness, Owen P., Jacobson, David A., Piston, David W., Hutton, John C., Powell, David R., O’Brien, Richard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400647/
https://www.ncbi.nlm.nih.gov/pubmed/22829903
http://dx.doi.org/10.1371/journal.pone.0040972

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