Concomitant administration of simvastatin with ivabradine in contrast to metoprolol intensifies slowing of heart rate in normo- and hypercholesterolemic rats

INTRODUCTION: β-Blockers play a significant role in therapeutic heart rate (HR) management and angina control. In patients who are unable to tolerate β-blockers ivabradine could be particularly useful. The aim of the study was to establish whether concomitant administration of simvastatin with ivabr...

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Detalles Bibliográficos
Autores principales: Owczarek, Jacek, Jasińska, Magdalena, Drożdż, Jarosław, Orszulak-Michalak, Daria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2012
Materias:
Experimental Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400921/
https://www.ncbi.nlm.nih.gov/pubmed/22852014
http://dx.doi.org/10.5114/aoms.2012.29411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400921/
https://www.ncbi.nlm.nih.gov/pubmed/22852014
http://dx.doi.org/10.5114/aoms.2012.29411

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