Cross-reactive broadly neutralizing antibodies: timing is everything

The recent surge of research into new broadly neutralizing antibodies in HIV-1 infection has recharged the field of HIV-1 vaccinology. In this review we discuss the currently known broadly neutralizing antibodies and focus on factors that may shape these antibodies in natural infection. We further d...

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Detalles Bibliográficos
Autores principales: Euler, Zelda, Schuitemaker, Hanneke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400945/
https://www.ncbi.nlm.nih.gov/pubmed/22833745
http://dx.doi.org/10.3389/fimmu.2012.00215
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author Euler, Zelda
Schuitemaker, Hanneke
author_facet Euler, Zelda
Schuitemaker, Hanneke
author_sort Euler, Zelda
collection PubMed
description The recent surge of research into new broadly neutralizing antibodies in HIV-1 infection has recharged the field of HIV-1 vaccinology. In this review we discuss the currently known broadly neutralizing antibodies and focus on factors that may shape these antibodies in natural infection. We further discuss the role of these antibodies in the clinical course of the infection and consider immunological obstacles in inducing broadly neutralizing antibodies with a vaccine.
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spelling pubmed-34009452012-07-25 Cross-reactive broadly neutralizing antibodies: timing is everything Euler, Zelda Schuitemaker, Hanneke Front Immunol Immunology The recent surge of research into new broadly neutralizing antibodies in HIV-1 infection has recharged the field of HIV-1 vaccinology. In this review we discuss the currently known broadly neutralizing antibodies and focus on factors that may shape these antibodies in natural infection. We further discuss the role of these antibodies in the clinical course of the infection and consider immunological obstacles in inducing broadly neutralizing antibodies with a vaccine. Frontiers Research Foundation 2012-07-20 /pmc/articles/PMC3400945/ /pubmed/22833745 http://dx.doi.org/10.3389/fimmu.2012.00215 Text en Copyright © 2012 Euler and Schuitemaker. http://www.frontiersin.org/licenseagreement This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/) , which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc.
spellingShingle Immunology
Euler, Zelda
Schuitemaker, Hanneke
Cross-reactive broadly neutralizing antibodies: timing is everything
title Cross-reactive broadly neutralizing antibodies: timing is everything
title_full Cross-reactive broadly neutralizing antibodies: timing is everything
title_fullStr Cross-reactive broadly neutralizing antibodies: timing is everything
title_full_unstemmed Cross-reactive broadly neutralizing antibodies: timing is everything
title_short Cross-reactive broadly neutralizing antibodies: timing is everything
title_sort cross-reactive broadly neutralizing antibodies: timing is everything
topic Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400945/
https://www.ncbi.nlm.nih.gov/pubmed/22833745
http://dx.doi.org/10.3389/fimmu.2012.00215
work_keys_str_mv AT eulerzelda crossreactivebroadlyneutralizingantibodiestimingiseverything
AT schuitemakerhanneke crossreactivebroadlyneutralizingantibodiestimingiseverything

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