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High-throughput analysis of epistasis in genome-wide association studies with BiForce

Motivation: Gene–gene interactions (epistasis) are thought to be important in shaping complex traits, but they have been under-explored in genome-wide association studies (GWAS) due to the computational challenge of enumerating billions of single nucleotide polymorphism (SNP) combinations. Fast scre...

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Detalles Bibliográficos
Autores principales:	Gyenesei, Attila, Moody, Jonathan, Semple, Colin A.M., Haley, Chris S., Wei, Wen-Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Original Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400955/ https://www.ncbi.nlm.nih.gov/pubmed/22618535 http://dx.doi.org/10.1093/bioinformatics/bts304

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