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miRcode: a map of putative microRNA target sites in the long non-coding transcriptome
Summary: Although small non-coding RNAs, such as microRNAs, have well-established functions in the cell, long non-coding RNAs (lncRNAs) have only recently started to emerge as abundant regulators of cell physiology, and their functions may be diverse. A small number of studies describe interactions...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400968/ https://www.ncbi.nlm.nih.gov/pubmed/22718787 http://dx.doi.org/10.1093/bioinformatics/bts344 |
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author | Jeggari, Ashwini Marks, Debora S Larsson, Erik |
author_facet | Jeggari, Ashwini Marks, Debora S Larsson, Erik |
author_sort | Jeggari, Ashwini |
collection | PubMed |
description | Summary: Although small non-coding RNAs, such as microRNAs, have well-established functions in the cell, long non-coding RNAs (lncRNAs) have only recently started to emerge as abundant regulators of cell physiology, and their functions may be diverse. A small number of studies describe interactions between small and lncRNAs, with lncRNAs acting either as inhibitory decoys or as regulatory targets of microRNAs, but such interactions are still poorly explored. To facilitate the study of microRNA–lncRNA interactions, we implemented miRcode: a comprehensive searchable map of putative microRNA target sites across the complete GENCODE annotated transcriptome, including 10 419 lncRNA genes in the current version. Availability: http://www.mircode.org Contact: erik.larsson@gu.se Supplementary Information: Supplementary data are available at Bioinformatics online. |
format | Online Article Text |
id | pubmed-3400968 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-34009682012-07-20 miRcode: a map of putative microRNA target sites in the long non-coding transcriptome Jeggari, Ashwini Marks, Debora S Larsson, Erik Bioinformatics Applications Note Summary: Although small non-coding RNAs, such as microRNAs, have well-established functions in the cell, long non-coding RNAs (lncRNAs) have only recently started to emerge as abundant regulators of cell physiology, and their functions may be diverse. A small number of studies describe interactions between small and lncRNAs, with lncRNAs acting either as inhibitory decoys or as regulatory targets of microRNAs, but such interactions are still poorly explored. To facilitate the study of microRNA–lncRNA interactions, we implemented miRcode: a comprehensive searchable map of putative microRNA target sites across the complete GENCODE annotated transcriptome, including 10 419 lncRNA genes in the current version. Availability: http://www.mircode.org Contact: erik.larsson@gu.se Supplementary Information: Supplementary data are available at Bioinformatics online. Oxford University Press 2012-08-01 2012-05-19 /pmc/articles/PMC3400968/ /pubmed/22718787 http://dx.doi.org/10.1093/bioinformatics/bts344 Text en © The Author(s) 2012. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Applications Note Jeggari, Ashwini Marks, Debora S Larsson, Erik miRcode: a map of putative microRNA target sites in the long non-coding transcriptome |
title | miRcode: a map of putative microRNA target sites in the long non-coding transcriptome |
title_full | miRcode: a map of putative microRNA target sites in the long non-coding transcriptome |
title_fullStr | miRcode: a map of putative microRNA target sites in the long non-coding transcriptome |
title_full_unstemmed | miRcode: a map of putative microRNA target sites in the long non-coding transcriptome |
title_short | miRcode: a map of putative microRNA target sites in the long non-coding transcriptome |
title_sort | mircode: a map of putative microrna target sites in the long non-coding transcriptome |
topic | Applications Note |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400968/ https://www.ncbi.nlm.nih.gov/pubmed/22718787 http://dx.doi.org/10.1093/bioinformatics/bts344 |
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