A High-Throughput Screen To Identify Inhibitors of ATP Homeostasis in Non-replicating Mycobacterium tuberculosis

[Image: see text] Growing evidence suggests that the presence of a subpopulation of hypoxic non-replicating, phenotypically drug-tolerant mycobacteria is responsible for the prolonged duration of tuberculosis treatment. The discovery of new antitubercular agents active against this subpopulation may...

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Detalles Bibliográficos
Autores principales: Mak, Puiying A., Rao, Srinivasa P. S., Ping Tan, Mai, Lin, Xiuhua, Chyba, Jason, Tay, Joann, Ng, Seow Hwee, Tan, Bee Huat, Cherian, Joseph, Duraiswamy, Jeyaraj, Bifani, Pablo, Lim, Vivian, Lee, Boon Heng, Ling Ma, Ngai, Beer, David, Thayalan, Pamela, Kuhen, Kelli, Chatterjee, Arnab, Supek, Frantisek, Glynne, Richard, Zheng, Jun, Boshoff, Helena I., Barry, Clifton E., Dick, Thomas, Pethe, Kevin, Camacho, Luis R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401038/
https://www.ncbi.nlm.nih.gov/pubmed/22500615
http://dx.doi.org/10.1021/cb2004884

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