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Long-Term Retinal PEDF Overexpression Prevents Neovascularization in a Murine Adult Model of Retinopathy

Neovascularization associated with diabetic retinopathy (DR) and other ocular disorders is a leading cause of visual impairment and adult-onset blindness. Currently available treatments are merely palliative and offer temporary solutions. Here, we tested the efficacy of antiangiogenic gene transfer...

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Detalles Bibliográficos
Autores principales: Haurigot, Virginia, Villacampa, Pilar, Ribera, Albert, Bosch, Assumpcio, Ramos, David, Ruberte, Jesus, Bosch, Fatima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401102/
https://www.ncbi.nlm.nih.gov/pubmed/22911805
http://dx.doi.org/10.1371/journal.pone.0041511