Cargando…

Long-Term Retinal PEDF Overexpression Prevents Neovascularization in a Murine Adult Model of Retinopathy

Neovascularization associated with diabetic retinopathy (DR) and other ocular disorders is a leading cause of visual impairment and adult-onset blindness. Currently available treatments are merely palliative and offer temporary solutions. Here, we tested the efficacy of antiangiogenic gene transfer...

Descripción completa

Detalles Bibliográficos
Autores principales:	Haurigot, Virginia, Villacampa, Pilar, Ribera, Albert, Bosch, Assumpcio, Ramos, David, Ruberte, Jesus, Bosch, Fatima
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401102/ https://www.ncbi.nlm.nih.gov/pubmed/22911805 http://dx.doi.org/10.1371/journal.pone.0041511

Ejemplares similares

Progressive neurologic and somatic disease in a novel mouse model of human mucopolysaccharidosis type IIIC
por: Marcó, Sara, et al.
Publicado: (2016)

Toward a gene therapy for neurological and somatic MPSIIIA
por: Haurigot, Virginia, et al.
Publicado: (2013)

PEDF mediates pathological neovascularization by regulating macrophage recruitment and polarization in the mouse model of oxygen-induced retinopathy
por: Gao, Sha, et al.
Publicado: (2017)

Accelerated oxygen-induced retinopathy is a reliable model of ischemia-induced retinal neovascularization
por: Villacampa, Pilar, et al.
Publicado: (2017)

A PEDF-Derived Peptide Inhibits Retinal Neovascularization and Blocks Mobilization of Bone Marrow-Derived Endothelial Progenitor Cells
por: Longeras, Richard, et al.
Publicado: (2012)

PEDF in Diabetic Retinopathy: A Protective Effect of Oxidative Stress
por: Zhu, Xiao-feng, et al.
Publicado: (2012)

Suppression of Retinal Neovascularization by Inhibition of Galectin-1 in a Murine Model of Oxygen-Induced Retinopathy
por: Yang, Ning, et al.
Publicado: (2017)

AAV-mediated pancreatic overexpression of Igf1 counteracts progression to autoimmune diabetes in mice
por: Mallol, Cristina, et al.
Publicado: (2017)

Receptors that bind to PEDF and their therapeutic roles in retinal diseases
por: Xu, Manhong, et al.
Publicado: (2023)

Mesenchymal stem cells overexpressing PEDF decrease the angiogenesis of gliomas
por: Wang, Qiaoshu, et al.
Publicado: (2013)

Peripheral Retinal Neovascularization with Vitreous Hemorrhage in HIV Retinopathy
por: Jiramongkolchai, Kim, et al.
Publicado: (2017)

Long-term follow-up of herpetic non-necrotizing retinopathy with occlusive retinal vasculitis and neovascularization
por: Albert, Kim, et al.
Publicado: (2015)

Adipose Tissue Overexpression of Vascular Endothelial Growth Factor Protects Against Diet-Induced Obesity and Insulin Resistance
por: Elias, Ivet, et al.
Publicado: (2012)

Long-Term Efficacy and Safety of Insulin and Glucokinase Gene Therapy for Diabetes: 8-Year Follow-Up in Dogs
por: Jaén, Maria Luisa, et al.
Publicado: (2017)

Hydrogen Sulfide Contributes to Retinal Neovascularization in Ischemia-Induced Retinopathy
por: Gersztenkorn, David, et al.
Publicado: (2016)

Harnessing retinal phagocytes to combat pathological neovascularization in ischemic retinopathies?
por: Klotzsche-von Ameln, Anne, et al.
Publicado: (2022)

VEGF-targeting drugs for the treatment of retinal neovascularization in diabetic retinopathy
por: Arrigo, Alessandro, et al.
Publicado: (2022)

Pemafibrate Prevents Retinal Pathological Neovascularization by Increasing FGF21 Level in a Murine Oxygen-Induced Retinopathy Model
por: Tomita, Yohei, et al.
Publicado: (2019)

Enhanced therapeutic effect of PEDF-loaded mesenchymal stem cell-derived small extracellular vesicles against oxygen-induced retinopathy through increased stability and penetrability of PEDF
por: Fan, Ruiyan, et al.
Publicado: (2023)

Treatment of Diabetes and Long-Term Survival After Insulin and Glucokinase Gene Therapy
por: Callejas, David, et al.
Publicado: (2013)

FGF21 gene therapy as treatment for obesity and insulin resistance
por: Jimenez, Veronica, et al.
Publicado: (2018)

Inhibitory effect of Samul-tang on retinal neovascularization in oxygen-induced retinopathy
por: Lee, Yun Mi, et al.
Publicado: (2015)

Maternally expressed gene 3 regulates retinal neovascularization in retinopathy of prematurity
por: Di, Yu, et al.
Publicado: (2021)

Microglia: The breakthrough to treat neovascularization and repair blood-retinal barrier in retinopathy
por: Fu, Xuefei, et al.
Publicado: (2023)

Relationship between pigment epithelium-derived factor (PEDF) and renal function in patients with diabetic retinopathy
por: Matsuyama, Kayako, et al.
Publicado: (2008)

Pigment Epithelium-Derived Factor (PEDF) Receptors Are Involved in Survival of Retinal Neurons
por: Bürger, Susanne, et al.
Publicado: (2020)

Scaffold-Free Retinal Pigment Epithelium Microtissues Exhibit Increased Release of PEDF
por: Al-Ani, Abdullah, et al.
Publicado: (2021)

Pressure-Induced Alterations in PEDF and PEDF-R Expression: Implications for Neuroprotective Signaling in Glaucoma
por: Lee, Sean J, et al.
Publicado: (2015)

Neovascularization in Purtscher’s retinopathy
por: Chan, Annie, et al.
Publicado: (2011)

Intravitreal bevacizumab treatment for retinal neovascularization and vitreous hemorrhage in proliferative diabetic retinopathy
por: El-Batarny, Ashraf M
Publicado: (2007)

Tenomodulin Inhibits Retinal Neovascularization in a Mouse Model of Oxygen-Induced Retinopathy
por: Wang, Wei, et al.
Publicado: (2012)

Sulodexide inhibits retinal neovascularization in a mouse model of oxygen-induced retinopathy
por: Jo, Hyoung, et al.
Publicado: (2014)

Ranibizumab-induced retinal reperfusion and regression of neovascularization in diabetic retinopathy: An angiographic illustration
por: Chandra, Shruti, et al.
Publicado: (2018)

Cedilanid inhibits retinal neovascularization in a mouse model of oxygen-induced retinopathy
por: Zhang, Jing Shang, et al.
Publicado: (2017)

Corrigendum: Maternally expressed gene 3 regulates retinal neovascularization in retinopathy of prematurity
Publicado: (2021)

PEDF and PEDF-derived peptide 44mer stimulate cardiac triglyceride degradation via ATGL
por: Zhang, Hao, et al.
Publicado: (2015)

Pigment Epithelium‐Derived Factor (PEDF) Improves Ischemic Cardiac Functional Reserve Through Decreasing Hypoxic Cardiomyocyte Contractility Through PEDF Receptor (PEDF‐R)
por: Lu, Peng, et al.
Publicado: (2016)

HMGA1 overexpression in adipose tissue impairs adipogenesis and prevents diet-induced obesity and insulin resistance
por: Arce-Cerezo, Altamira, et al.
Publicado: (2015)

Megalencephalic Leukoencephalopathy: Insights Into Pathophysiology and Perspectives for Therapy
por: Bosch, Assumpció, et al.
Publicado: (2021)

Association of the Pattern of Retinal Capillary Non-Perfusion and Vascular Leakage with Retinal Neovascularization in Proliferative Diabetic Retinopathy
por: Jung, Eric E., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_8kiru8vmo0qk1007lt45998dp2