Hepatitis B Viral DNA Decline at Loss of HBeAg Is Mainly Explained by Reduced cccDNA Load – Down-Regulated Transcription of PgRNA Has Limited Impact

BACKGROUND: Quantification of hepatitis B virus (HBV) DNA and surface antigen (HBsAg) serum levels have become increasingly important for the assessment of clinical stage and response to treatment for chronic hepatitis B. Effective immune clearance results in reduction of viremia by 4–5 log units an...

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Detalles Bibliográficos
Autores principales: Malmström, Sebastian, Larsson, Simon B., Hannoun, Charles, Lindh, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401194/
https://www.ncbi.nlm.nih.gov/pubmed/22911677
http://dx.doi.org/10.1371/journal.pone.0036349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401194/
https://www.ncbi.nlm.nih.gov/pubmed/22911677
http://dx.doi.org/10.1371/journal.pone.0036349

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