Polyglutamine Aggregate Structure In Vitro and In Vivo; New Avenues for Coherent Anti-Stokes Raman Scattering Microscopy

Coherent anti-Stokes Raman scattering (CARS) microscopy is applied for the first time for the evaluation of the protein secondary structure of polyglutamine (polyQ) aggregates in vivo. Our approach demonstrates the potential for translating information about protein structure that has been obtained...

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Detalles Bibliográficos
Autores principales: Perney, Nicolas M., Braddick, Lucy, Jurna, Martin, Garbacik, Erik T., Offerhaus, Herman L., Serpell, Louise C., Blanch, Ewan, Holden-Dye, Lindy, Brocklesby, William S., Melvin, Tracy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401212/
https://www.ncbi.nlm.nih.gov/pubmed/22911702
http://dx.doi.org/10.1371/journal.pone.0040536

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