ATM-Dependent Downregulation of USP7/HAUSP by PPM1G Activates p53 Response to DNA Damage

The deubiquitylation enzyme USP7/HAUSP plays a major role in regulating genome stability and cancer prevention by controlling the key proteins involved in the DNA damage response. Despite this important role in controlling other proteins, USP7 itself has not been recognized as a target for regulatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Khoronenkova, Svetlana V., Dianova, Irina I., Ternette, Nicola, Kessler, Benedikt M., Parsons, Jason L., Dianov, Grigory L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401373/
https://www.ncbi.nlm.nih.gov/pubmed/22361354
http://dx.doi.org/10.1016/j.molcel.2012.01.021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401373/
https://www.ncbi.nlm.nih.gov/pubmed/22361354
http://dx.doi.org/10.1016/j.molcel.2012.01.021

Ejemplares similares