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Buffering and proteolysis are induced by segmental monosomy in Drosophila melanogaster

Variation in the number of individual chromosomes (chromosomal aneuploidy) or chromosome segments (segmental aneuploidy) is associated with developmental abnormalities and reduced fitness in all species examined; it is the leading cause of miscarriages and mental retardation and a hallmark of cancer...

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Detalles Bibliográficos
Autores principales: Lundberg, Lina E., Figueiredo, Margarida L. A., Stenberg, Per, Larsson, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401434/
https://www.ncbi.nlm.nih.gov/pubmed/22434883
http://dx.doi.org/10.1093/nar/gks245