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Role of SUMO modification of human PCNA at stalled replication fork

DNA double-strand breaks (DSBs) can be generated not only by reactive agents but also as a result of replication fork collapse at unrepaired DNA lesions. Whereas ubiquitylation of proliferating cell nuclear antigen (PCNA) facilitates damage bypass, modification of yeast PCNA by small ubiquitin-like...

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Detalles Bibliográficos
Autores principales: Gali, Himabindu, Juhasz, Szilvia, Morocz, Monika, Hajdu, Ildiko, Fatyol, Karoly, Szukacsov, Valeria, Burkovics, Peter, Haracska, Lajos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401441/
https://www.ncbi.nlm.nih.gov/pubmed/22457066
http://dx.doi.org/10.1093/nar/gks256