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Mixture of differentially tagged Tol2 transposons accelerates conditional disruption of a broad spectrum of genes in mouse embryonic stem cells
Among the insertional mutagenesis techniques used in the current international knockout mouse project (KOMP) on the inactivation of all mouse genes in embryonic stem (ES) cells, random gene trapping has been playing a major role. Gene-targeting experiments have also been performed to individually an...
Autores principales: | Mayasari, N. Ika, Mukougawa, Keiko, Shigeoka, Toshiaki, Kawakami, Koichi, Kawaichi, Masashi, Ishida, Yasumasa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401447/ https://www.ncbi.nlm.nih.gov/pubmed/22447447 http://dx.doi.org/10.1093/nar/gks262 |
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