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Master regulatory GATA transcription factors: mechanistic principles and emerging links to hematologic malignancies

Numerous examples exist of how disrupting the actions of physiological regulators of blood cell development yields hematologic malignancies. The master regulator of hematopoietic stem/progenitor cells GATA-2 was cloned almost 20 years ago, and elegant genetic analyses demonstrated its essential func...

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Detalles Bibliográficos
Autores principales:	Bresnick, Emery H., Katsumura, Koichi R., Lee, Hsiang-Ying, Johnson, Kirby D., Perkins, Archibald S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Survey and Summary
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401466/ https://www.ncbi.nlm.nih.gov/pubmed/22492510 http://dx.doi.org/10.1093/nar/gks281

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