Magnetic resonance imaging in pantothenate kinase-2-associated neurodegeneration

Pantothenate kinase-2-associated neurodegeneration (PKAN) is a rare autosomal recessive pediatric neurodegenerative disorder characterized by rigidity, dystonia, impaired postural reflexes, and progressive dementia. On T2-weighted magnetic resonance imaging images, marked low signal intensity is see...

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Autores principales: Singh, Paramdeep, Saggar, Kavita, Kaur, Maneet, Pannu, Davinder Singh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Neuroimaging
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401648/
https://www.ncbi.nlm.nih.gov/pubmed/22837773
http://dx.doi.org/10.4103/1817-1745.97618
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author Singh, Paramdeep
Saggar, Kavita
Kaur, Maneet
Pannu, Davinder Singh
author_facet Singh, Paramdeep
Saggar, Kavita
Kaur, Maneet
Pannu, Davinder Singh
author_sort Singh, Paramdeep
collection PubMed
description Pantothenate kinase-2-associated neurodegeneration (PKAN) is a rare autosomal recessive pediatric neurodegenerative disorder characterized by rigidity, dystonia, impaired postural reflexes, and progressive dementia. On T2-weighted magnetic resonance imaging images, marked low signal intensity is seen in the globus pallidus. This low signal intensity surrounds a central region of high signal intensity in the anteromedial globus pallidus, giving an eye-of-the-tiger appearance.
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spelling pubmed-34016482012-07-26 Magnetic resonance imaging in pantothenate kinase-2-associated neurodegeneration Singh, Paramdeep Saggar, Kavita Kaur, Maneet Pannu, Davinder Singh J Pediatr Neurosci Neuroimaging Pantothenate kinase-2-associated neurodegeneration (PKAN) is a rare autosomal recessive pediatric neurodegenerative disorder characterized by rigidity, dystonia, impaired postural reflexes, and progressive dementia. On T2-weighted magnetic resonance imaging images, marked low signal intensity is seen in the globus pallidus. This low signal intensity surrounds a central region of high signal intensity in the anteromedial globus pallidus, giving an eye-of-the-tiger appearance. Medknow Publications & Media Pvt Ltd 2012 /pmc/articles/PMC3401648/ /pubmed/22837773 http://dx.doi.org/10.4103/1817-1745.97618 Text en Copyright: © Journal of Pediatric Neurosciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Neuroimaging
Singh, Paramdeep
Saggar, Kavita
Kaur, Maneet
Pannu, Davinder Singh
Magnetic resonance imaging in pantothenate kinase-2-associated neurodegeneration
title Magnetic resonance imaging in pantothenate kinase-2-associated neurodegeneration
title_full Magnetic resonance imaging in pantothenate kinase-2-associated neurodegeneration
title_fullStr Magnetic resonance imaging in pantothenate kinase-2-associated neurodegeneration
title_full_unstemmed Magnetic resonance imaging in pantothenate kinase-2-associated neurodegeneration
title_short Magnetic resonance imaging in pantothenate kinase-2-associated neurodegeneration
title_sort magnetic resonance imaging in pantothenate kinase-2-associated neurodegeneration
topic Neuroimaging
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401648/
https://www.ncbi.nlm.nih.gov/pubmed/22837773
http://dx.doi.org/10.4103/1817-1745.97618
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