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Incidental detection of hyperfunctioning thyroid cancer metastases in patients presenting with thyrotoxicosis
Thyrotoxicosis due to functioning metastases from thyroid cancer is rare. It also presents a therapeutic challenge, as both the metastatic cancer and thyrotoxicosis need to be treated. We present here two cases of thyrotoxicosis which on a routine (99m)Tc-pertechnetate thyroid scan showed extrathyro...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401771/ https://www.ncbi.nlm.nih.gov/pubmed/22837931 http://dx.doi.org/10.4103/2230-8210.98028 |
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author | Damle, Nishikant A. Bal, Chandrasekhar Kumar, Praveen Soundararajan, Ramya Subbarao, Kiran |
author_facet | Damle, Nishikant A. Bal, Chandrasekhar Kumar, Praveen Soundararajan, Ramya Subbarao, Kiran |
author_sort | Damle, Nishikant A. |
collection | PubMed |
description | Thyrotoxicosis due to functioning metastases from thyroid cancer is rare. It also presents a therapeutic challenge, as both the metastatic cancer and thyrotoxicosis need to be treated. We present here two cases of thyrotoxicosis which on a routine (99m)Tc-pertechnetate thyroid scan showed extrathyroidal foci of uptake. Two patients who initially presented with thyrotoxicosis underwent a routine thyroid scan. Abnormal uptake in the shoulder was incidentally noted, which prompted us to do a whole body pertechnetate scan in the same sitting, which revealed extensive hyperfunctioning metastases in the lungs and bones. We also discuss the ‘Flip Flop’ phenomenon in thyroid cancer, which was seen in our case. This report emphasizes the importance of evaluating the abnormal foci of uptake seen on a routine thyroid scan. |
format | Online Article Text |
id | pubmed-3401771 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-34017712012-07-26 Incidental detection of hyperfunctioning thyroid cancer metastases in patients presenting with thyrotoxicosis Damle, Nishikant A. Bal, Chandrasekhar Kumar, Praveen Soundararajan, Ramya Subbarao, Kiran Indian J Endocrinol Metab Case-Based Literature Review Thyrotoxicosis due to functioning metastases from thyroid cancer is rare. It also presents a therapeutic challenge, as both the metastatic cancer and thyrotoxicosis need to be treated. We present here two cases of thyrotoxicosis which on a routine (99m)Tc-pertechnetate thyroid scan showed extrathyroidal foci of uptake. Two patients who initially presented with thyrotoxicosis underwent a routine thyroid scan. Abnormal uptake in the shoulder was incidentally noted, which prompted us to do a whole body pertechnetate scan in the same sitting, which revealed extensive hyperfunctioning metastases in the lungs and bones. We also discuss the ‘Flip Flop’ phenomenon in thyroid cancer, which was seen in our case. This report emphasizes the importance of evaluating the abnormal foci of uptake seen on a routine thyroid scan. Medknow Publications & Media Pvt Ltd 2012 /pmc/articles/PMC3401771/ /pubmed/22837931 http://dx.doi.org/10.4103/2230-8210.98028 Text en Copyright: © Indian Journal of Endocrinology and Metabolism http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case-Based Literature Review Damle, Nishikant A. Bal, Chandrasekhar Kumar, Praveen Soundararajan, Ramya Subbarao, Kiran Incidental detection of hyperfunctioning thyroid cancer metastases in patients presenting with thyrotoxicosis |
title | Incidental detection of hyperfunctioning thyroid cancer metastases in patients presenting with thyrotoxicosis |
title_full | Incidental detection of hyperfunctioning thyroid cancer metastases in patients presenting with thyrotoxicosis |
title_fullStr | Incidental detection of hyperfunctioning thyroid cancer metastases in patients presenting with thyrotoxicosis |
title_full_unstemmed | Incidental detection of hyperfunctioning thyroid cancer metastases in patients presenting with thyrotoxicosis |
title_short | Incidental detection of hyperfunctioning thyroid cancer metastases in patients presenting with thyrotoxicosis |
title_sort | incidental detection of hyperfunctioning thyroid cancer metastases in patients presenting with thyrotoxicosis |
topic | Case-Based Literature Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401771/ https://www.ncbi.nlm.nih.gov/pubmed/22837931 http://dx.doi.org/10.4103/2230-8210.98028 |
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