Cargando…
Furegrelate, a thromboxane synthase inhibitor, blunts the development of pulmonary arterial hypertension in neonatal piglets
The development of pulmonary arterial hypertension (PAH) in pediatric patients has been linked to the production of the arachidonic acid metabolite, thromboxane A(2) (TxA(2)). The present study evaluated the therapeutic effect of furegrelate sodium, a thromboxane synthase inhibitor, on the developme...
Autores principales: | Hirenallur-S., Dinesh K., Detweiler, Neil D., Haworth, Steven T., Leming, Jeaninne T., Gordon, John B., Rusch, Nancy J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401873/ https://www.ncbi.nlm.nih.gov/pubmed/22837860 http://dx.doi.org/10.4103/2045-8932.97605 |
Ejemplares similares
-
Expression of thromboxane synthase, TBXAS1 and the thromboxane A2 receptor, TBXA2R, in human breast cancer
por: Watkins, Gareth, et al.
Publicado: (2005) -
Lack of Thromboxane Synthase Prevents Hypertension and Fetal Growth Restriction after High Salt Treatment during Pregnancy
por: Pai, Chen-Hsueh, et al.
Publicado: (2016) -
Direct Molecular Fishing of New Protein Partners for Human Thromboxane Synthase
por: Svirid, A. V., et al.
Publicado: (2017) -
Thromboxane promotes smooth muscle phenotype commitment but not remodeling of hypoxic neonatal pulmonary artery
por: Postolow, Fabiana, et al.
Publicado: (2015) -
Examination of thromboxane synthase as a prognostic factor and therapeutic target in non-small cell lung cancer
por: Cathcart, Mary-Clare, et al.
Publicado: (2011)