Metabolomic analysis of bone morphogenetic protein receptor type 2 mutations in human pulmonary endothelium reveals widespread metabolic reprogramming

Pulmonary arterial hypertension (PAH) is a progressive and fatal disease of the lung vasculature for which the molecular etiologies are unclear. Specific metabolic alterations have been identified in animal models and in PAH patients, though existing data focus mainly on abnormalities of glucose hom...

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Detalles Bibliográficos
Autores principales: Fessel, Joshua P., Hamid, Rizwan, Wittmann, Bryan M., Robinson, Linda J., Blackwell, Tom, Tada, Yuji, Tanabe, Nobuhiro, Tatsumi, Koichiro, Hemnes, Anna R., West, James D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401874/
https://www.ncbi.nlm.nih.gov/pubmed/22837861
http://dx.doi.org/10.4103/2045-8932.97606

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401874/
https://www.ncbi.nlm.nih.gov/pubmed/22837861
http://dx.doi.org/10.4103/2045-8932.97606

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