Unlocking Holocentric Chromosomes: New Perspectives from Comparative and Functional Genomics?

The presence of chromosomes with diffuse centromeres (holocentric chromosomes) has been reported in several taxa since more than fifty years, but a full understanding of their origin is still lacking. Comparative and functional genomics are nowadays furnishing new data to better understand holocentr...

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Detalles Bibliográficos
Autores principales: Mandrioli, Mauro, Manicardi, Gian Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401891/
https://www.ncbi.nlm.nih.gov/pubmed/23372420
http://dx.doi.org/10.2174/138920212801619250
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author Mandrioli, Mauro
Manicardi, Gian Carlo
author_facet Mandrioli, Mauro
Manicardi, Gian Carlo
author_sort Mandrioli, Mauro
collection PubMed
description The presence of chromosomes with diffuse centromeres (holocentric chromosomes) has been reported in several taxa since more than fifty years, but a full understanding of their origin is still lacking. Comparative and functional genomics are nowadays furnishing new data to better understand holocentric chromosome evolution thus opening new perspectives to analyse karyotype rearrangements in species with holocentric chromosomes in particular evidencing unusual common features, such as the uniform GC content and gene distribution along chromosomes.
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spelling pubmed-34018912013-02-01 Unlocking Holocentric Chromosomes: New Perspectives from Comparative and Functional Genomics? Mandrioli, Mauro Manicardi, Gian Carlo Curr Genomics Article The presence of chromosomes with diffuse centromeres (holocentric chromosomes) has been reported in several taxa since more than fifty years, but a full understanding of their origin is still lacking. Comparative and functional genomics are nowadays furnishing new data to better understand holocentric chromosome evolution thus opening new perspectives to analyse karyotype rearrangements in species with holocentric chromosomes in particular evidencing unusual common features, such as the uniform GC content and gene distribution along chromosomes. Bentham Science Publishers 2012-08 2012-08 /pmc/articles/PMC3401891/ /pubmed/23372420 http://dx.doi.org/10.2174/138920212801619250 Text en ©2012 Bentham Science Publishers http://creativecommons.org/licenses/by/2.5/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.5/), which permits unrestrictive use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Article
Mandrioli, Mauro
Manicardi, Gian Carlo
Unlocking Holocentric Chromosomes: New Perspectives from Comparative and Functional Genomics?
title Unlocking Holocentric Chromosomes: New Perspectives from Comparative and Functional Genomics?
title_full Unlocking Holocentric Chromosomes: New Perspectives from Comparative and Functional Genomics?
title_fullStr Unlocking Holocentric Chromosomes: New Perspectives from Comparative and Functional Genomics?
title_full_unstemmed Unlocking Holocentric Chromosomes: New Perspectives from Comparative and Functional Genomics?
title_short Unlocking Holocentric Chromosomes: New Perspectives from Comparative and Functional Genomics?
title_sort unlocking holocentric chromosomes: new perspectives from comparative and functional genomics?
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401891/
https://www.ncbi.nlm.nih.gov/pubmed/23372420
http://dx.doi.org/10.2174/138920212801619250
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