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Functional Impact of Sequence Alterations Found in BRCA1 Promoter/5'UTR Region in Breast/Ovarian Cancer Families from Upper Silesia, Poland
The 5' region of BRCA1 contains multiple regulatory sequences flanking the two alternative promoters α and β and two alternative, non-coding exons, 1a and 1b. Aberrations within the 5' region BRCA1 (encompassing two alternative promoters α and β and exons 1a and 1b) may be associated with...
Autores principales: | Pamuła, Jolanta, Krześniak, Małgorzata, Zientek, Helena, Pękala, Wioletta, Rusin, Marek, Grzybowska, Ewa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401915/ https://www.ncbi.nlm.nih.gov/pubmed/20222999 http://dx.doi.org/10.1186/1897-4287-4-1-20 |
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