Cargando…

Deregulation of FoxM1b leads to tumour metastasis

The forkhead box M1b (FoxM1b) transcription factor is over-expressed in human cancers, and its expression often correlates with poor prognosis. Previously, using conditional knockout strains, we showed that FoxM1b is essential for hepatocellular carcinoma (HCC) development. However, over-expression...

Descripción completa

Detalles Bibliográficos
Autores principales:	Park, Hyun Jung, Gusarova, Galina, Wang, Zebin, Carr, Janai R, Li, Jing, Kim, Ki-Hyun, Qiu, Jin, Park, Yoon-Dong, Williamson, Peter R, Hay, Nissim, Tyner, Angela L, Lau, Lester F, Costa, Robert H, Raychaudhuri, Pradip
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	WILEY-VCH Verlag 2011
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401999/ https://www.ncbi.nlm.nih.gov/pubmed/21204266 http://dx.doi.org/10.1002/emmm.201000107

Ejemplares similares

Plk1 Regulates the Repressor Function of FoxM1b by inhibiting its Interaction with the Retinoblastoma Protein
por: Mukhopadhyay, Nishit K., et al.
Publicado: (2017)

Author Correction: Plk1 Regulates the Repressor Function of FoxM1b by inhibiting its Interaction with the Retinoblastoma Protein
por: Mukhopadhyay, Nishit K., et al.
Publicado: (2018)

FoxM1 is Upregulated in Osteosarcoma and Inhibition of FoxM1 Decreases Osteosarcoma Cell Proliferation, Migration, and Invasion
por: Zhu, Xia, et al.
Publicado: (2020)

Aberrantly high activation of a FoxM1–STMN1 axis contributes to progression and tumorigenesis in FoxM1-driven cancers
por: Liu, Jun, et al.
Publicado: (2021)

FoxM1 Is a General Target for Proteasome Inhibitors
por: Bhat, Uppoor G., et al.
Publicado: (2009)

FoxM1 Induced Paclitaxel Resistance via Activation of the FoxM1/PHB1/RAF-MEK-ERK Pathway and Enhancement of the ABCA2 Transporter
por: Huang, Chao, et al.
Publicado: (2019)

Overexpression of FoxM1 predicts poor prognosis of intrahepatic cholangiocarcinoma
por: Liu, Lingyun, et al.
Publicado: (2018)

Structure of the FoxM1 DNA-recognition domain bound to a promoter sequence
por: Littler, D. R., et al.
Publicado: (2010)

Deregulated immune cell recruitment orchestrated by FOXM1 impairs human diabetic wound healing
por: Sawaya, Andrew P., et al.
Publicado: (2020)

MicroRNA-320a suppresses tumour cell proliferation and invasion of renal cancer cells by targeting FoxM1
por: Zhao, Shiyue, et al.
Publicado: (2018)

Deregulation of the FOXM1 target gene network and its coregulatory partners in oesophageal adenocarcinoma
por: Wiseman, Elizabeth F, et al.
Publicado: (2015)

Novel functions of FoxM1: from molecular mechanisms to cancer therapy
por: Alvarez-Fernández, Mónica, et al.
Publicado: (2013)

Effect of taxol on the expression of FoxM1 ovarian cancer-associated gene
por: LIU, ZENG, et al.
Publicado: (2016)

FoxM1 is a promising candidate target in the treatment of breast cancer
por: Lu, Xiao-Feng, et al.
Publicado: (2017)

An order-to-disorder structural switch activates the FoxM1 transcription factor
por: Marceau, Aimee H, et al.
Publicado: (2019)

FoxM1 knockdown enhanced radiosensitivity of esophageal cancer by inducing apoptosis
por: Qin, Qin, et al.
Publicado: (2023)

Identification of FOXM1 as a therapeutic target in B-cell lineage acute lymphoblastic leukaemia
por: Buchner, Maike, et al.
Publicado: (2015)

Erratum to: ‘Deregulation of the FOXM1 target gene network and its coregulatory partners in oesophageal adenocarcinoma’
por: Wiseman, Elizabeth F., et al.
Publicado: (2016)

Thiazole Antibiotics Target FoxM1 and Induce Apoptosis in Human Cancer Cells
por: Bhat, Uppoor G., et al.
Publicado: (2009)

Non-viral FoxM1 gene delivery to hepatocytes enhances liver repopulation
por: Xiang, D, et al.
Publicado: (2014)

CDI Exerts Anti-Tumor Effects by Blocking the FoxM1-DNA Interaction
por: Jang, Woo Dae, et al.
Publicado: (2022)

Invasive FoxM1 phosphorylated by PLK1 induces the polarization of tumor-associated macrophages to promote immune escape and metastasis, amplified by IFITM1
por: Xu, Rong, et al.
Publicado: (2023)

FoxM1 Promotes Stemness and Radio-Resistance of Glioblastoma by Regulating the Master Stem Cell Regulator Sox2
por: Lee, Yeri, et al.
Publicado: (2015)

Analysis of survivin, XIAP and FoxM1 as potential chemoresistance factors in breast cancer cells
por: Moraes, Gabriela N, et al.
Publicado: (2013)

FoxM1 Promotes Glioma Cells Progression by Up-Regulating Anxa1 Expression
por: Cheng, Shi-Xiang, et al.
Publicado: (2013)

FoxM1 transactivates PTTG1 and promotes colorectal cancer cell migration and invasion
por: Zheng, Yun, et al.
Publicado: (2015)

FoxM1 Directs STAT3 Expression Essential for Human Endometrial Stromal Decidualization
por: Jiang, Yaling, et al.
Publicado: (2015)

BET Bromodomain Inhibition as a Therapeutic Strategy in Ovarian Cancer by Downregulating FoxM1
por: Zhang, Zhenfeng, et al.
Publicado: (2016)

FoxM1 is associated with metastasis in colorectal cancer through induction of the epithelial-mesenchymal transition
por: Fei, Bao-Ying, et al.
Publicado: (2017)

Clinicopathological and prognostic significance of FoxM1 in hepatocellular carcinoma patients: a meta-analysis
por: Liang, Chaojie, et al.
Publicado: (2018)

FoxM1 promotes epithelial-mesenchymal transition of hepatocellular carcinoma by targeting Snai1
por: Yu, Chun-Peng, et al.
Publicado: (2017)

FoxM1 Promotes Cell Proliferation, Invasion, and Stem Cell Properties in Nasopharyngeal Carcinoma
por: Luo, Weiren, et al.
Publicado: (2018)

Aberrant ASPM expression mediated by transcriptional regulation of FoxM1 promotes the progression of gliomas
por: Zeng, Wen‐Jing, et al.
Publicado: (2020)

A Cdh1–FoxM1–Apc axis controls muscle development and regeneration
por: Chen, Zhe, et al.
Publicado: (2020)

Silencing of FoxM1 blocks growth, migration and invasion of papillary thyroid carcinoma cells
por: Wang, Xiaotao, et al.
Publicado: (2020)

A narrative review of research progress on FoxM1 in breast cancer carcinogenesis and therapeutics
por: Zhang, Yan-Ling, et al.
Publicado: (2021)

HPV Infection is Associated with FoxM1 Overexpression in Dysplastic Changes of Sinonasal Inverted Papilloma
por: Rachmadi, Lisnawati, et al.
Publicado: (2022)

Neuronal signals regulate obesity induced β-cell proliferation by FoxM1 dependent mechanism
por: Yamamoto, Junpei, et al.
Publicado: (2017)

A lignan induces lysosomal dependent degradation of FoxM1 protein to suppress β-catenin nuclear translocation
por: Dong, Guang-zhi, et al.
Publicado: (2017)

β-Cell Proliferation, but Not Neogenesis, Following 60% Partial Pancreatectomy Is Impaired in the Absence of FoxM1
por: Ackermann Misfeldt, Amanda, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_o2m23s6q97qvs01ususfki6ooo