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Comparison with ancestral diets suggests dense acellular carbohydrates promote an inflammatory microbiota, and may be the primary dietary cause of leptin resistance and obesity
A novel hypothesis of obesity is suggested by consideration of diet-related inflammation and evolutionary medicine. The obese homeostatically guard their elevated weight. In rodent models of high-fat diet-induced obesity, leptin resistance is seen initially at vagal afferents, blunting the actions o...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402009/ https://www.ncbi.nlm.nih.gov/pubmed/22826636 http://dx.doi.org/10.2147/DMSO.S33473 |