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Autoantigen-Specific B-Cell Depletion Overcomes Failed Immune Tolerance in Type 1 Diabetes

Eliminating autoantigen-specific B cells is an attractive alternative to global B-cell depletion for autoimmune disease treatment. To identify the potential for targeting a key autoimmune B-cell specificity in type 1 diabetes, insulin-binding B cells were tracked within a polyclonal repertoire using...

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Detalles Bibliográficos
Autores principales:	Henry, Rachel A., Kendall, Peggy L., Thomas, James W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2012
Materias:	Immunology and Transplantation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402296/ https://www.ncbi.nlm.nih.gov/pubmed/22698916 http://dx.doi.org/10.2337/db11-1746

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