Loss of Pdk1-Foxo1 Signaling in Myeloid Cells Predisposes to Adipose Tissue Inflammation and Insulin Resistance

Chronic inflammation in adipose tissue contributes to obesity-related insulin resistance. The 3-phosphoinositide-dependent protein kinase 1 (Pdk1)/forkhead transcription factor (Foxo1) pathway is important in regulating glucose and energy homeostasis, but little is known about this pathway in adipos...

Descripción completa

Detalles Bibliográficos
Autores principales: Kawano, Yoshinaga, Nakae, Jun, Watanabe, Nobuyuki, Fujisaka, Shiho, Iskandar, Kristy, Sekioka, Risa, Hayashi, Yoshitake, Tobe, Kazuyuki, Kasuga, Masato, Noda, Tetsuo, Yoshimura, Akihiko, Onodera, Masafumi, Itoh, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402298/
https://www.ncbi.nlm.nih.gov/pubmed/22586579
http://dx.doi.org/10.2337/db11-0770

Ejemplares similares

Ejemplares similares