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Changing Metabolic Signatures of Amino Acids and Lipids During the Prediabetic Period in a Pig Model With Impaired Incretin Function and Reduced β-Cell Mass

Diabetes is generally diagnosed too late. Therefore, biomarkers indicating early stages of β-cell dysfunction and mass reduction would facilitate timely counteraction. Transgenic pigs expressing a dominant-negative glucose-dependent insulinotropic polypeptide receptor (GIPR(dn)) reveal progressive d...

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Detalles Bibliográficos
Autores principales:	Renner, Simone, Römisch-Margl, Werner, Prehn, Cornelia, Krebs, Stefan, Adamski, Jerzy, Göke, Burkhard, Blum, Helmut, Suhre, Karsten, Roscher, Adelbert A., Wolf, Eckhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2012
Materias:	Genetics/Genomes/Proteomics/Metabolomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402307/ https://www.ncbi.nlm.nih.gov/pubmed/22492530 http://dx.doi.org/10.2337/db11-1133

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