Cargando…

Inhibition of Gelatinase B (Matrix Metalloprotease-9) Activity Reduces Cellular Inflammation and Restores Function of Transplanted Pancreatic Islets

Islet transplantation provides an approach to compensate for loss of insulin-producing cells in patients with type 1 diabetes. However, the intraportal route of transplantation is associated with instant inflammatory reactions to the graft and subsequent islet destruction as well. Although matrix me...

Descripción completa

Detalles Bibliográficos
Autores principales: Lingwal, Neelam, Padmasekar, Manju, Samikannu, Balaji, Bretzel, Reinhard G., Preissner, Klaus T., Linn, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402316/
https://www.ncbi.nlm.nih.gov/pubmed/22586582
http://dx.doi.org/10.2337/db11-1143