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Inhibition of Gelatinase B (Matrix Metalloprotease-9) Activity Reduces Cellular Inflammation and Restores Function of Transplanted Pancreatic Islets

Islet transplantation provides an approach to compensate for loss of insulin-producing cells in patients with type 1 diabetes. However, the intraportal route of transplantation is associated with instant inflammatory reactions to the graft and subsequent islet destruction as well. Although matrix me...

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Detalles Bibliográficos
Autores principales:	Lingwal, Neelam, Padmasekar, Manju, Samikannu, Balaji, Bretzel, Reinhard G., Preissner, Klaus T., Linn, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2012
Materias:	Immunology and Transplantation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402316/ https://www.ncbi.nlm.nih.gov/pubmed/22586582 http://dx.doi.org/10.2337/db11-1143

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