Cargando…

Steady-State Brain Glucose Concentrations During Hypoglycemia in Healthy Humans and Patients With Type 1 Diabetes

The objective of this study was to investigate the relationship between plasma and brain glucose levels during euglycemia and hypoglycemia in healthy subjects and patients with type 1 diabetes mellitus (T1DM). Hyperinsulinemic euglycemic (5 mmol/L) and hypoglycemic (3 mmol/L) [1-(13)C]glucose clamps...

Descripción completa

Detalles Bibliográficos
Autores principales:	van de Ven, Kim C.C., van der Graaf, Marinette, Tack, Cees J., Heerschap, Arend, de Galan, Bastiaan E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2012
Materias:	Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402320/ https://www.ncbi.nlm.nih.gov/pubmed/22688331 http://dx.doi.org/10.2337/db11-1778

Ejemplares similares

Effect of Acute Hypoglycemia on Human Cerebral Glucose Metabolism Measured by (13)C Magnetic Resonance Spectroscopy
por: van de Ven, Kim C.C., et al.
Publicado: (2011)

Effect of lactate administration on brain lactate levels during hypoglycemia in patients with type 1 diabetes
por: Wiegers, Evita C, et al.
Publicado: (2018)

Brain glucose metabolism during hypoglycemia in type 1 diabetes: insights from functional and metabolic neuroimaging studies
por: Rooijackers, Hanne M. M., et al.
Publicado: (2015)

Effect of lactate administration on cerebral blood flow during hypoglycemia in people with type 1 diabetes
por: van Meijel, Lian A, et al.
Publicado: (2022)

Elevated brain glutamate levels in type 1 diabetes: correlations with glycaemic control and age of disease onset but not with hypoglycaemia awareness status
por: Wiegers, Evita C., et al.
Publicado: (2019)

The effect of acute exercise on glycogen synthesis rate in obese subjects studied by (13)C MRS
por: van der Graaf, Marinette, et al.
Publicado: (2010)

Automatic frequency and phase alignment of in vivo J-difference-edited MR spectra by frequency domain correlation
por: Wiegers, Evita C., et al.
Publicado: (2017)

Altered brain high-energy phosphate metabolism in mild Alzheimer's disease: A 3-dimensional (31)P MR spectroscopic imaging study
por: Rijpma, Anne, et al.
Publicado: (2018)

Dissociation Between Hormonal Counterregulatory Responses and Cerebral Glucose Metabolism During Hypoglycemia
por: Lee, John J., et al.
Publicado: (2017)

Needle-Free Jet Injection of Rapid-Acting Insulin Improves Early Postprandial Glucose Control in Patients With Diabetes
por: Engwerda, Elsemiek E.C., et al.
Publicado: (2013)

Naloxone, but Not Valsartan, Preserves Responses to Hypoglycemia After Antecedent Hypoglycemia: Role of Metabolic Reprogramming in Counterregulatory Failure
por: Poplawski, Michal M., et al.
Publicado: (2011)

Effect of Hypoglycemia on Heart Rate Variability in People with Type 1 Diabetes and Impaired Awareness of Hypoglycemia
por: Koeneman, Mats, et al.
Publicado: (2021)

Effects of Gastric Bypass Surgery on the Brain: Simultaneous Assessment of Glucose Uptake, Blood Flow, Neural Activity, and Cognitive Function During Normo- and Hypoglycemia
por: Almby, Kristina E., et al.
Publicado: (2021)

Ghrelin Suppresses Glucose-Stimulated Insulin Secretion and Deteriorates Glucose Tolerance in Healthy Humans
por: Tong, Jenny, et al.
Publicado: (2010)

Effect of short‐term use of dapagliflozin on impaired awareness of hypoglycaemia in people with type 1 diabetes
por: van Meijel, Lian A., et al.
Publicado: (2021)

THU276 The Use of Continuous Glucose Monitors for Management of Postbariatric Hypoglycemia
por: Jani, Shivani, et al.
Publicado: (2023)

The medical food Souvenaid affects brain phospholipid metabolism in mild Alzheimer’s disease: results from a randomized controlled trial
por: Rijpma, Anne, et al.
Publicado: (2017)

Simultaneous Recording of the Uptake and Conversion of Glucose and Choline in Tumors by Deuterium Metabolic Imaging
por: Veltien, Andor, et al.
Publicado: (2021)

Modulation of β-Adrenergic Receptors in the Ventromedial Hypothalamus Influences Counterregulatory Responses to Hypoglycemia
por: Szepietowska, Barbara, et al.
Publicado: (2011)

Antecedent Hypoglycemia Impairs Autonomic Cardiovascular Function: Implications for Rigorous Glycemic Control
por: Adler, Gail K., et al.
Publicado: (2009)

Pharmacokinetic and Pharmacodynamic Variability of Insulin When Administered by Jet Injection
por: Engwerda, Elsemiek E. C., et al.
Publicado: (2017)

Glucose concentrations after insulin‐induced hypoglycemia and glycemic variability in healthy and diabetic cats
por: Zini, Eric, et al.
Publicado: (2018)

Metabolomic, hormonal and physiological responses to hypoglycemia versus euglycemia during exercise in adults with type 1 diabetes
por: McCarthy, Olivia, et al.
Publicado: (2020)

Consistent Effects of Hypoglycemia on Cognitive Function in People With or Without Diabetes
por: Verhulst, Clementine E.M., et al.
Publicado: (2022)

Magnetic Resonance Spectroscopic Imaging and Volumetric Measurements of the Brain in Patients with Postcancer Fatigue: A Randomized Controlled Trial
por: Prinsen, Hetty, et al.
Publicado: (2013)

In vivo magnetic resonance spectroscopy: basic methodology and clinical applications
por: van der Graaf, Marinette
Publicado: (2009)

Consumption of low doses of fat prevents the postprandial rise in chylomicron particle concentration and remnant accumulation in healthy normolipidaemic males
por: James, Anthony P., et al.
Publicado: (2012)

MON-184 Hypoglycemia During Mixed Meal Tolerance Testing and Early Glucose Dysregulation in Cystic Fibrosis
por: Kilberg, Marissa, et al.
Publicado: (2019)

SAT164 Hypoglycemia Risk And Glucose Parameters In Pregnant Women With Or Without Diabetes During Fasting Ramadan
por: Alamoudi, Reem Mohammad, et al.
Publicado: (2023)

Hypoglycemia-Sensing Neurons of the Ventromedial Hypothalamus Require AMPK-Induced Txn2 Expression but Are Dispensable for Physiological Counterregulation
por: Quenneville, Simon, et al.
Publicado: (2020)

Liver Enzymes Are Associated With Hepatic Insulin Resistance, Insulin Secretion, and Glucagon Concentration in Healthy Men and Women
por: Bonnet, Fabrice, et al.
Publicado: (2011)

Systemic inflammation down-regulates glyoxalase-1 expression: an experimental study in healthy males
por: G.H. Driessen, Rob, et al.
Publicado: (2021)

High prevalence of impaired awareness of hypoglycemia and severe hypoglycemia among people with insulin-treated type 2 diabetes: The Dutch Diabetes Pearl Cohort
por: van Meijel, Lian A, et al.
Publicado: (2020)

Effect of Chronic Hyperglycemia on Glucose Metabolism in Subjects With Normal Glucose Tolerance
por: Shannon, Chris, et al.
Publicado: (2018)

Glucose Transporter-1 in the Hypothalamic Glial Cells Mediates Glucose Sensing to Regulate Glucose Production In Vivo
por: Chari, Madhu, et al.
Publicado: (2011)

Improved Pharmacokinetic and Pharmacodynamic Profile of Rapid-Acting Insulin Using Needle-Free Jet Injection Technology
por: Engwerda, Elsemiek E.C., et al.
Publicado: (2011)

Non-Islet Cell Tumor Hypoglycemia: A Rare Cause of Hypoglycemia in Pulmonary Sarcomatoid Cancer
por: Legare, Timothy B, et al.
Publicado: (2017)

Simple Reason for Hypoglycemia: ACE Inhibitor-induced Severe Recurrent Hypoglycemia in a Nondiabetic Patient
por: Elshimy, Ghada, et al.
Publicado: (2019)

Effects of Insulin on Brain Glucose Metabolism in Impaired Glucose Tolerance
por: Hirvonen, Jussi, et al.
Publicado: (2011)

Should Target Glucose Values Be Increased to Avoid Severe Hypoglycemia? Real-World Data Say “No.”
por: Welsh, John, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ejns8p13uk0hg7an9tf1vigrbp