Oxidation of Fatty Acids Is the Source of Increased Mitochondrial Reactive Oxygen Species Production in Kidney Cortical Tubules in Early Diabetes

Mitochondrial reactive oxygen species (ROS) cause kidney damage in diabetes. We investigated the source and site of ROS production by kidney cortical tubule mitochondria in streptozotocin-induced type 1 diabetes in rats. In diabetic mitochondria, the increased amounts and activities of selective fat...

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Detalles Bibliográficos
Autores principales: Rosca, Mariana G., Vazquez, Edwin J., Chen, Qun, Kerner, Janos, Kern, Timothy S., Hoppel, Charles L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Complications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402323/
https://www.ncbi.nlm.nih.gov/pubmed/22586586
http://dx.doi.org/10.2337/db11-1437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402323/
https://www.ncbi.nlm.nih.gov/pubmed/22586586
http://dx.doi.org/10.2337/db11-1437

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