Cargando…

Absence of PTHrP Nuclear Localization and Carboxyl Terminus Sequences Leads to Abnormal Brain Development and Function

We assessed whether the nuclear localization sequences (NLS) and C terminus of parathyroid hormone-related protein (PTHrP) play critical roles in brain development and function. We used histology, immunohistochemistry, histomorphometry, Western blots and electrophysiological recordings to compare th...

Descripción completa

Detalles Bibliográficos
Autores principales: Gu, Zhen, Liu, Yahong, Zhang, Yongjie, Jin, Shulei, Chen, Qi, Goltzman, David, Karaplis, Andrew, Miao, Dengshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402381/
https://www.ncbi.nlm.nih.gov/pubmed/22844494
http://dx.doi.org/10.1371/journal.pone.0041542