MC-12, an Annexin A1-Based Peptide, Is Effective in the Treatment of Experimental Colitis

Annexin A1 (ANXA1) inhibits NF-κB, a key regulator of inflammation, the common pathophysiological mechanism of inflammatory bowel diseases (IBD). MC-12, an ANXA1-based tripeptide, suppresses NF-κB activation. Here, we determined the efficacy of MC-12 in the control of IBD. Mice with colitis induced...

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Detalles Bibliográficos
Autores principales: Ouyang, Nengtai, Zhu, Caihua, Zhou, Dingying, Nie, Ting, Go, Mae F., Richards, Robert J., Rigas, Basil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402399/
https://www.ncbi.nlm.nih.gov/pubmed/22844504
http://dx.doi.org/10.1371/journal.pone.0041585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402399/
https://www.ncbi.nlm.nih.gov/pubmed/22844504
http://dx.doi.org/10.1371/journal.pone.0041585

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