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Markers of Endogenous Desaturase Activity and Risk of Coronary Heart Disease in the CAREMA Cohort Study
BACKGROUND: Intakes of n-3 polyunsaturated fatty acids (PUFAs), especially EPA (C20∶5n-3) and DHA (C22∶6n-3), are known to prevent fatal coronary heart disease (CHD). The effects of n-6 PUFAs including arachidonic acid (C20∶4n-6), however, remain unclear. δ-5 and δ-6 desaturases are rate-limiting en...
Autores principales: | Lu, Yingchang, Vaarhorst, Anika, Merry, Audrey H. H., Dollé, Martijn E. T., Hovenier, Robert, Imholz, Sandra, Schouten, Leo J., Heijmans, Bastiaan T., Müller, Michael, Slagboom, P. Eline, van den Brandt, Piet A., Gorgels, Anton P. M., Boer, Jolanda M. A., Feskens, Edith J. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402436/ https://www.ncbi.nlm.nih.gov/pubmed/22911844 http://dx.doi.org/10.1371/journal.pone.0041681 |
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