The T Box Transcription Factor TBX2 Promotes Epithelial-Mesenchymal Transition and Invasion of Normal and Malignant Breast Epithelial Cells

The T box transcription factor TBX2, a master regulator of organogenesis, is aberrantly amplified in aggressive human epithelial cancers. While it has been shown that overexpression of TBX2 can bypass senescence, a failsafe mechanism against cancer, its potential role in tumor invasion has remained...

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Detalles Bibliográficos
Autores principales: Wang, Bin, Lindley, Linsey E., Fernandez-Vega, Virneliz, Rieger, Megan E., Sims, Andrew H., Briegel, Karoline J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402503/
https://www.ncbi.nlm.nih.gov/pubmed/22844464
http://dx.doi.org/10.1371/journal.pone.0041355

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