Mycobacterium tuberculosis Complex Enhances Susceptibility of CD4 T Cells to HIV through a TLR2-Mediated Pathway

Among HIV-infected individuals, co-infection with Mycobacterium tuberculosis is associated with faster progression to AIDS. We investigated the hypothesis that M. bovis BCG and M. tuberculosis (Mtb complex) could enhance susceptibility of CD4+ cells to HIV infection. Peripheral blood mononuclear cel...

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Detalles Bibliográficos
Autores principales: Thayil, Seema M., Ho, Ya-Chi, Bollinger, Robert C., Blankson, Joel N., Siliciano, Robert F., Karakousis, Petros C., Page, Kathleen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402510/
https://www.ncbi.nlm.nih.gov/pubmed/22844428
http://dx.doi.org/10.1371/journal.pone.0041093