Guanidylation and Tail Effects in Cationic Antimicrobial Lipopeptoids

BACKGROUND: Cationic antimicrobial peptides (CAMPs) are attractive scaffolds for the next generation of antimicrobial compounds, due to their broad spectrum of activity against multi-drug resistant bacteria and the reduced fitness of CAMP-insensitive mutants. Unfortunately, they are limited by poor...

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Detalles Bibliográficos
Autores principales: Findlay, Brandon, Szelemej, Paul, Zhanel, George G., Schweizer, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402541/
https://www.ncbi.nlm.nih.gov/pubmed/22844435
http://dx.doi.org/10.1371/journal.pone.0041141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402541/
https://www.ncbi.nlm.nih.gov/pubmed/22844435
http://dx.doi.org/10.1371/journal.pone.0041141

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