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Guanidylation and Tail Effects in Cationic Antimicrobial Lipopeptoids
BACKGROUND: Cationic antimicrobial peptides (CAMPs) are attractive scaffolds for the next generation of antimicrobial compounds, due to their broad spectrum of activity against multi-drug resistant bacteria and the reduced fitness of CAMP-insensitive mutants. Unfortunately, they are limited by poor...
Autores principales: | Findlay, Brandon, Szelemej, Paul, Zhanel, George G., Schweizer, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402541/ https://www.ncbi.nlm.nih.gov/pubmed/22844435 http://dx.doi.org/10.1371/journal.pone.0041141 |
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